Cost-efficient vaccination of foxes ( Vulpes vulpes ) against rabies and the need for a new baiting strategy
Identifieur interne : 000857 ( Istex/Checkpoint ); précédent : 000856; suivant : 000858Cost-efficient vaccination of foxes ( Vulpes vulpes ) against rabies and the need for a new baiting strategy
Auteurs : Thomas Selhorst [Allemagne] ; Hans-Hermann Thulke [Allemagne] ; Thomas Müller [Allemagne]Source :
- Preventive Veterinary Medicine [ 0167-5877 ] ; 2001.
Descripteurs français
- Wicri :
- topic : Rage.
English descriptors
Abstract
In this study, ecological models, optimisation algorithms and threshold analysis were linked to develop oral-vaccination strategies against rabies in fox populations. It is important that such strategies are cost-efficient and resistant to environmental conditions which would lessen their success. The model validation shows that the ecological models used are suited to predict the proportion of tetracycline- (TC) marked foxes in the course of time. This figure indicates the proportion of foxes which had at least one contact to vaccine baits, and is based on the design of the vaccination strategy (i.e. the number and timing of vaccination campaigns and the number of baits used per square kilometre and campaign). The design of a vaccination strategy also determines the costs. It is the combination of ecological models and optimisation algorithms that helped us to design a vaccination strategy which is capable of achieving a continuous rate of >70% of TC-marked foxes within an analytical horizon of 3 years at low costs. Compared to the standard strategy (baseline comparator), the improved strategy incurs just over half of the cost while almost doubling the number of weeks during which the proportion of TC-marked foxes is >70%. In the improved strategy, June is recommended as the time for bait distribution. The standard strategy, however, avoids summer months (because high temperatures reduce the durability of the baits) which again leads to a reduction of the bait intake by the foxes. Using threshold analysis, we examined the effect of a reduced durability of the baits on the design of the improved vaccination strategy. We concluded that distribution of baits in June was optimal given that the durability of baits is above a threshold of 7 days.
Url:
DOI: 10.1016/S0167-5877(01)00209-4
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
ISTEX:7C8B6D037AC5F19DEA33FF030F27295A86160ABDLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Cost-efficient vaccination of foxes ( Vulpes vulpes ) against rabies and the need for a new baiting strategy</title><author><name sortKey="Selhorst, Thomas" sort="Selhorst, Thomas" uniqKey="Selhorst T" first="Thomas" last="Selhorst">Thomas Selhorst</name></author><author><name sortKey="Thulke, Hans Hermann" sort="Thulke, Hans Hermann" uniqKey="Thulke H" first="Hans-Hermann" last="Thulke">Hans-Hermann Thulke</name></author><author><name sortKey="Muller, Thomas" sort="Muller, Thomas" uniqKey="Muller T" first="Thomas" last="Müller">Thomas Müller</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:7C8B6D037AC5F19DEA33FF030F27295A86160ABD</idno><date when="2001" year="2001">2001</date><idno type="doi">10.1016/S0167-5877(01)00209-4</idno><idno type="url">https://api.istex.fr/document/7C8B6D037AC5F19DEA33FF030F27295A86160ABD/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001253</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001253</idno><idno type="wicri:Area/Istex/Curation">001252</idno><idno type="wicri:Area/Istex/Checkpoint">000857</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000857</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Cost-efficient vaccination of foxes ( Vulpes vulpes ) against rabies and the need for a new baiting strategy</title><author><name sortKey="Selhorst, Thomas" sort="Selhorst, Thomas" uniqKey="Selhorst T" first="Thomas" last="Selhorst">Thomas Selhorst</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Federal Research Centre for Virus Diseases of Animals, WHO Collaborating Centre for rabies in Central and Eastern Europe, Institute for Epidemiology, Seetr. 55, D-16868 Wusterhausen</wicri:regionArea><wicri:noRegion>16868 Wusterhausen</wicri:noRegion><wicri:noRegion>D-16868 Wusterhausen</wicri:noRegion></affiliation><affiliation></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Allemagne</country></affiliation></author><author><name sortKey="Thulke, Hans Hermann" sort="Thulke, Hans Hermann" uniqKey="Thulke H" first="Hans-Hermann" last="Thulke">Hans-Hermann Thulke</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Ecological Modelling, UFZ — Centre for Environmental Research Leipzig-Halle, D-04318 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Muller, Thomas" sort="Muller, Thomas" uniqKey="Muller T" first="Thomas" last="Müller">Thomas Müller</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Federal Research Centre for Virus Diseases of Animals, Institute for Epidemiological Diagnostics, D-16868 Wusterhausen</wicri:regionArea><wicri:noRegion>16868 Wusterhausen</wicri:noRegion><wicri:noRegion>D-16868 Wusterhausen</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Preventive Veterinary Medicine</title><title level="j" type="abbrev">PREVET</title><idno type="ISSN">0167-5877</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="2001">2001</date><biblScope unit="volume">51</biblScope><biblScope unit="issue">1–2</biblScope><biblScope unit="page" from="95">95</biblScope><biblScope unit="page" to="109">109</biblScope></imprint><idno type="ISSN">0167-5877</idno></series><idno type="istex">7C8B6D037AC5F19DEA33FF030F27295A86160ABD</idno><idno type="DOI">10.1016/S0167-5877(01)00209-4</idno><idno type="PII">S0167-5877(01)00209-4</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0167-5877</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Modelling</term><term>Optimisation</term><term>Rabies</term><term>Red fox</term><term>Threshold analysis</term><term>Vaccination strategies</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Rage</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In this study, ecological models, optimisation algorithms and threshold analysis were linked to develop oral-vaccination strategies against rabies in fox populations. It is important that such strategies are cost-efficient and resistant to environmental conditions which would lessen their success. The model validation shows that the ecological models used are suited to predict the proportion of tetracycline- (TC) marked foxes in the course of time. This figure indicates the proportion of foxes which had at least one contact to vaccine baits, and is based on the design of the vaccination strategy (i.e. the number and timing of vaccination campaigns and the number of baits used per square kilometre and campaign). The design of a vaccination strategy also determines the costs. It is the combination of ecological models and optimisation algorithms that helped us to design a vaccination strategy which is capable of achieving a continuous rate of >70% of TC-marked foxes within an analytical horizon of 3 years at low costs. Compared to the standard strategy (baseline comparator), the improved strategy incurs just over half of the cost while almost doubling the number of weeks during which the proportion of TC-marked foxes is >70%. In the improved strategy, June is recommended as the time for bait distribution. The standard strategy, however, avoids summer months (because high temperatures reduce the durability of the baits) which again leads to a reduction of the bait intake by the foxes. Using threshold analysis, we examined the effect of a reduced durability of the baits on the design of the improved vaccination strategy. We concluded that distribution of baits in June was optimal given that the durability of baits is above a threshold of 7 days.</div></front></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>District de Leipzig</li><li>Saxe (Land)</li></region><settlement><li>Leipzig</li></settlement></list><tree><country name="Allemagne"><noRegion><name sortKey="Selhorst, Thomas" sort="Selhorst, Thomas" uniqKey="Selhorst T" first="Thomas" last="Selhorst">Thomas Selhorst</name></noRegion><name sortKey="Muller, Thomas" sort="Muller, Thomas" uniqKey="Muller T" first="Thomas" last="Müller">Thomas Müller</name><name sortKey="Selhorst, Thomas" sort="Selhorst, Thomas" uniqKey="Selhorst T" first="Thomas" last="Selhorst">Thomas Selhorst</name><name sortKey="Thulke, Hans Hermann" sort="Thulke, Hans Hermann" uniqKey="Thulke H" first="Hans-Hermann" last="Thulke">Hans-Hermann Thulke</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Bois/explor/RenardV1/Data/Istex/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000857 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Checkpoint/biblio.hfd -nk 000857 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Bois
|area= RenardV1
|flux= Istex
|étape= Checkpoint
|type= RBID
|clé= ISTEX:7C8B6D037AC5F19DEA33FF030F27295A86160ABD
|texte= Cost-efficient vaccination of foxes ( Vulpes vulpes ) against rabies and the need for a new baiting strategy
}}
| This area was generated with Dilib version V0.6.27. |  |